NEW YORK (360Dx) – A team led by researchers at the University of Illinois at Urbana-Champaign have developed a new microscopy method that could improve label-free imaging of living tissues.

Called SLAM (simultaneous label-free autofluorescence-multiharmonic) microscopy, the approach is a version of label-free multiphoton intravital microscopy (LFM IVM), which uses a light source to stimulate molecules in a tissue of interest and microscopy to observe the autofluorescence of these molecules, allowing researchers to obtain cellular information without needing exogenous labels.