variants of unknown significance
The firm's test for Lynch Syndrome determines the presence of variants in the DNA mismatch repair pathway.
New ESHG Recommendations for Clinical Whole-Genome Sequencing Show Differences From US Guidelines
Previous guidelines for clinical NGS, published by the society in collaboration with EuroGenTest in 2016, focused mainly on whole-exome sequencing.
Quest Diagnostics Win in Wrongful Death Case Reveals Ongoing Challenges for Variant Classification
Williams v Quest/Athena struck a nerve with the genetic testing community by probing what the standard of care is and ought to be for variant classification.
Patients Having Ovaries Removed Without Clear Genetic, Medical Rationale, Study Suggests
Results from the PROMPT registry presented at ASCO showed that 10 to 15 percent of women with variants in genes not linked to ovarian cancer had oophorectomies.
Quest Files Motion for Summary Judgment in Wrongful Death Lawsuit
Following a lengthy discovery period, the lab is asking a South Carolina federal district court to find in its favor and decide that its negligence did not result in the death of Williams' son.