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drug resistance

The new center will focus on liquid biopsy technologies for tracking treatment response and for monitoring patients with minimal residual disease.

The study authors said that many cases of drug resistance remained undetected due to inaccurate tests, resulting in more deaths from incorrect treatment. 

The institutes will send patients samples to Resolution Bioscience, which will sequence circulating tumor DNA to identify the genetic causes of drug resistance.

Researchers at the University of Cologne were able to show that the results of the 30-minute ICT test were concordant with standard methods, which can take up to 72 hours.

The PCR assay is intended to help detect TB-causing bacteria and determine if it harbors mutations associated with isoniazid and rifampicin resistance.

Using a protocol developed at the University of Oxford, the researchers hope that nanopore sequencing can aid diagnosis and drug resistance profiling in remote areas.

The firm plans to eventually market a direct-from-blood platform that uses infrared spectrometry to identify drug-resistant pathogens within 20 minutes.

The funding will accelerate development of the firm's RaPID diagnostic platform to identify pathogens and drug resistance directly from blood.

Drug-breakpoint updates should provide a clearer regulatory path for AST system makers but it's only one step in the fight against antimicrobial resistance, said Romney Humphries of Accelerate Diagnostics.

Russian companies supported by Skolkovo will gain access to the AMRC's R&D expertise, international connections, and funding mechanisms.

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