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drug resistance

The test is the fourth assay on the firm's Revogene system and it detects five common genetic causes of drug resistance.

A display at a booth at ECCMID where antimicrobial resistance was a major theme.

Industry executives said that clinical needs associated with antimicrobial resistance and sepsis are generating more interest in AST technologies.

The PCR-based Carba assay is designed to detect and differentiate bacterial gene sequences that are associated with resistance to carbapenem antibiotics.

The funds will be used to support development and early marketing of a rapid test system for antibiotic resistance targeting patients with suspected sepsis.

The new center will focus on liquid biopsy technologies for tracking treatment response and for monitoring patients with minimal residual disease.

The study authors said that many cases of drug resistance remained undetected due to inaccurate tests, resulting in more deaths from incorrect treatment. 

The institutes will send patients samples to Resolution Bioscience, which will sequence circulating tumor DNA to identify the genetic causes of drug resistance.

Researchers at the University of Cologne were able to show that the results of the 30-minute ICT test were concordant with standard methods, which can take up to 72 hours.

The PCR assay is intended to help detect TB-causing bacteria and determine if it harbors mutations associated with isoniazid and rifampicin resistance.

Using a protocol developed at the University of Oxford, the researchers hope that nanopore sequencing can aid diagnosis and drug resistance profiling in remote areas.

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