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April 24, 2019
Sponsored by
Biocrates

Metabolomics Analyses to Elucidate Systemic Processes in Human Health and Disease

Genome Webinar

Head of the Genome Analysis Center, Head of Molecular Endocrinology; Helmholtz Center Munich

This webinar provides a wide-ranging overview of the promise for metabolomics in studying human health and disease, as well as its potential for integration with other -omics disciplines.

Our speaker, Dr. Jerzy Adamski of the Helmholtz Center Munich, reviews current approaches in targeted and non-targeted metabolomics, highlighting differences in methodology, coverage, advantages, and disadvantages of either approach. 

This webinar puts a special emphasis on the universal applications of broad targeted metabolomics assays, which have shown promise in delineating factors contributing to the clinical phenotype, including intrinsic and environment-related processes. Dr. Adamski also touchs upon the benefits of calculating metabolite sums and ratios along the most important metabolic pathways.

The acknowledgement of the importance of host-microbiota interaction warrants a look at how metabolomics can help this rather young research field move beyond associations between disease risk and microbial genetics, and towards a more thorough functional understanding of the involved processes. For this purpose, Dr. Adamski highlights selected metabolic pathways that are known to be associated with gut microbiota and affect health via direct metabolic and immune-related effects.

Finally, Dr. Adamski discusses how metabolomics can integrate with other -omics technologies, providing examples of how metabolomics has enhanced genome-wide association studies, among others.

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