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Staff Scientist, Assay Development

Organization
Element Biosciences
Job Location
10655 Sorrento Valley Road, Suite 100
San Diego, CA 92121
United States
Benefits

We offer excellent benefits, which include a 401K plan, competitive health benefits, flexible vacation, and equity incentives. 

Job Description

Staff scientist contributor for exciting well-funded and long-term multi-venture backed Life Sciences and IVD start-up company.  Determines and analyzes design approaches for biochemical assays and applications.  Resolves DOE challenges for complex biochemical systems from both a biophysical and biochemical perspective. Well versed in the areas of optics, microscopy, and microfluidics as related to n-dimensional biochemical/biophysical scientific high throughput surface assays. Develops advanced methods/techniques for testing and evaluation. Designs, builds, and tests prototype equipment and products. Provides project leadership, technical consultation, work direction, and training to junior personnel. Works without appreciable direction on assigned projects/programs. Participates in determining objectives of assignments.

Duties and Responsibilities:

 

  • Design and understand fundamental biochemical assays as relate to pre-steady state enzyme mechanisms.
  • Design and understand fundamental biochemical assays as related to clinical assays for biomarker discovery.
  • Apply fundamental understanding optical design, motion control, fluidics, and electronics to implement automation for HT biochemical assay instrumentation.
  • Design, develop and execute experimental plan independently as well as in a small team.
  • Interact closely with engineers to develop comprehensive solutions for high throughput assay development and screening.
  • Participate in intellectual property creation.
  • Provide guidance and work assignment to technicians
Requirements

Relevant Skills:

 

Must have experience in the following technical areas:

  • High throughput assay development and DOE design.
  • Thorough knowledge of biochemical assays and applications to solve and understand complex biochemical systems
  • Hands-on laboratory skills for assembly, alignment, calibration, and evaluation of optical systems.

Desired experience in the following technical areas:

  • Protein purification and engineering.
  • Enzyme kinetics modeling and studies
  • Familiarity with JMP software.
  • Flow cells/microfluidics consumables impacting instrumentation design.
  • Image processing and complex data analysis for HT assay data output.
  • Experience in liquid handling systems.
  • Programming skills:  Matlab, Java, IDE, R.

Leadership and management skills

  • Success in this position requires frequent communication with peers and management. These relationships must be built on respect, integrity, cooperation, teamwork and professionalism.
  • Excellent problem solving and project management skills.
  • Ability to lead program teams.

Qualifications:

Education training and work related experience:

  • Doctoral degree (Ph.D.) in chemistry, biochemistry, biophysics, physical chemistry, physics, bioengineering or a related discipline.
  • 3+ years industry related experience and/or training;
How to Apply

Please send resume to ebaker@elembio.com

About Our Organization

Element Biosciences is a multi-disciplinary startup focused on innovating genetic analysis tools for the research and diagnostic markets. The Company's technology will broaden the end user experience through improved data quality and simplified workflows to benefit discoveries and diagnosis in healthcare.

We foster an environment such that all people are afforded the freedom to pursue their passions without regard to race, color, religion, national or ethnic origin, gender (including pregnancy), sexual orientation, gender identity or expression, age, disability, veteran status or any other characteristics protected by law.