Close Menu

Staff Reliability Engineer

Pacific Biosciences
Job Location
1305 O'Brien Drive
Menlo Park, CA 94025
United States


PacBio’s success was built on innovation. Our future success is dependent on the continuation of this tradition, and we can only achieve this goal by working in teams that foster diversity, creativity, and high performance. Our employees largely contribute to our success, and we understand the value that a comprehensive benefits package holds for our employees and their families.

While specific benefit offerings vary by country, we strive to provide:

  • Competitive coverage. Plans that reflect current market practice and the level and type of benefits that companies like PacBio provide.
  • Flexibility. PacBio recognizes the diversity of our employee population and has benefit choices that meet a wide variety of needs.
  • Quality. PacBio strives to contract with leading health and benefits carrier partners who maintain high standards of service.
  • Financial protection. Insurance and retirement plans that help keep you in good financial shape.

The following summarizes programs offered in the U.S.


Healthcare and Insurance Plans

  • Choice of HMO, PPO, and High Deductible medical plans
  • Health Savings Account, which includes employer funding
  • Comprehensive dental and vision plans
  • Employee assistance program
  • Company-paid accident and life insurance programs, with options to purchase additional coverage at group coverage rates to further support and protect employees and their families
  • Company-paid travel accidental death and dismemberment plan
  • Company-paid short and long-term disability insurance
  • Flexible Spending Accounts for Health Care and Dependent Care Reimbursements

Commuting Benefits

  • Pre-Tax Commuter Transit and Parking Spending Accounts
  • Shuttle service to and from local Caltrain stations
  • Bike lockers and shower facilities
  • Electric car charging stations (FOC)

Financial Planning

  • Competitive pay including incentive and equity programs
  • Employee Stock Purchase Plan (ESPP) offers eligible team members the opportunity to purchase company stock at a discount
  • 401(k) Retirement plan

Time Off Programs

  • We welcome flexible work arrangements, subject to specifics of the role
  • Generous holiday schedule
  • Vacation accrual up to 15 days per year
  • Paid sick leave up to 80 hours per year
  • New Parent Leave


  • Wellness program with valuable health incentive opportunities
  • Annual health fair
  • Vaccination clinics
  • Fully equipped on-campus fitness center
  • Certified instructor-led fitness classes

Professional Development

  • Course curriculum available through LinkedIn Learning
  • Quarterly patent awards program

Additional Perks

  • Onsite cafeteria
  • Food trucks
  • Coffee bars
  • BAGs (happy hours)
  • BBQs
Job Description

Staff Reliability Engineer

Pacific Biosciences™ is seeking a Staff Reliability Engineer with a strong customer focus to support New Product Development as well as Sustaining activities for our SMRT™ sequencing technology and related platforms. The ability to communicate with component Suppliers and out-sourced service providers both during and post-design, interact with development engineering and internal support teams, and communicate results to diverse audiences are important aspects of this role. This individual will be working in a fast-paced development environment, interacting with scientists and engineers from a wide variety of backgrounds. The position will be based in Menlo Park, California.



  • Develop a detailed understanding of all technologies necessary to support our instruments [electrical, mechanical, optical, computer, software, chemical].
  • Generate comprehensive FMEA packages for all aspects of new product designs. Included in this deliverable are formalized tracking of all test activities and maintenance of failure mode mitigation/retirement records.
  • Gather internal as well as customer experience data to identify the highest impact failure modes and conditions which require improvements.
  • Develop and Manage HALT as well as other Reliability test programs and methodologies
  • Perform failure analysis on module-level as well as system-level problems in efforts to isolate root cause and work with Design teams to provide solutions.
  • Work directly with component and module-level Suppliers as well as R&D subject matter experts to create predictive reliability models for module-level as well as System-level reliability predictions.
  • Apply industry knowledge in providing guidance to cross-functional technical teams in efforts to improve instrument quality and reliability.
  • In partnership with Quality Assurance, ensure the products are compliant to applicable Regulatory and Compliance standards.
  • Define and use numerous tools and scripts to gather data necessary to make intelligent product design decisions.


  • Post-product launch, represent the voice of the customer in all aspects of your job.
  • In partnership with Quality Assurance, ensure the products remain compliant to applicable Regulatory and Compliance standards.
  • Define and use numerous tools and scripts to gather field data necessary for updating demonstrated reliability figures; use this updated information to manage escalations as well as drive product change.
  • Lead project teams in selection and management of escalations and redesign activities.
  • Present team or department findings and metrics in various forums.
  • Provide guidance to R&D on product reliability testing and analysis to demonstrate the product will achieve its reliability goals.
  • Model the impact of the field issues on warranty cost.

All listed tasks and responsibilities are deemed as essential functions to this position; however, business conditions may require reasonable accommodations for additional tasks and responsibilities.


Position Requirements: 

  • Minimum of a BS in Electrical Engineering, Computer Science, Mechanical Engineering, or Biomedical Engineering, or related discipline.  M.S. in a technical discipline a plus.
  • 10+ years of experience in roles directly supporting product design, new product introduction, product quality and reliability, preferably in a systems company.
  • Experience in Statistics (Weibull Analysis, MTBF, BellCore), Reliability Test (HALT, ALT, ORT) and System/Module/Component level FMEA development for Electrical/Mechanical/Optical sub-systems.
  • Good understanding of development processes associated with complex Systems design.
  • Excellent understanding of risk management principals.
  • Excellent verbal and written communication skills.
  • Excellent troubleshooting abilities.
  • Demonstrates excellent documentation skills; exhibits thoroughness and attention to detail to ensure that job tasks are completed with a high level of quality.
  • Ability to work independently and collaboratively with cross-functional team members.
  • Strong time management, organizational and planning skills are essential.
  • Experience in operating next-generation DNA sequencing instruments and assays a plus.

All qualified applicants will receive consideration for employment without regard to race, sex, color, religion, national origin, protected veteran status, or on the basis of disability, gender identity, and sexual orientation.

How to Apply

Please apply at:


About Our Organization

PacBio is the leading provider of high-quality sequencing of genomes, transcriptomes & epigenomes.

Edit Page