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Senior Bioinformatician (NGS Application Scientist)

Job Location
185 Dartmouth St Unit 502 Boston,
Boston, MA 02116
United States
  • A flexible, friendly and international working environment with a collaborative atmosphere
  • An exciting company mission that brings together science and technology to directly impact the lives of patients with life threatening illness.
  • A fast-growing company with plenty of opportunity for personal growth and development
  • A hard technical challenge to solve with exciting modern technology - cloud computing, Big Data, DevOps, machine learning
Job Description

In our journey to impact on patients' lives, we are currently looking for a Senior Bioinformatician to join the Bundle Solution Development team in the Bioinformatics and Data Science department of SOPHiA GENETICS in Denver USA.

SOPHiA GENETICS provides a Data Driven Platform for NGS-based clinical diagnostic products. As a Senior Bioinformatician you will explore diverse clinical genomic datasets to assess the performance of currently available NGS assays on market and help develop the next generation of SOPHiA GENETICS bioinformatics products.

We are seeking a candidate with extensive experience of conducting genomic projects involving DNA/RNA bioinformatics pipelines in an academic or industry setting. It would be a great plus if you are familiar with capture-based target sequencing approach applied in the field of oncology. Your main roles would include assessing the quality of diverse NGS datasets and exploring factors that affect their performances in terms of coverage uniformity, library conversation rate, variant calling (i.e., that lead to false positive or false negative results) and etc. All of the achievements would essentially help develop or improve SOPHiA GENETICS NGS-based applications.

  • PhD and/or several years postdoc or industry experience in bioinformatics and NGS data analysis and proven to conduct independent research.
  • Strong publication record in the field of genomics
  • Extensive experience with exploratory data analysis and visualization using either R or Python.
  • Strong background in cancer cell biology will be a plus
  • Capacity to work in a fast-paced and multidisciplinary environment
How to Apply


About Our Organization

Ranked among the "50 Smartest Companies" in the world according to the MIT Technology Review, SOPHiA GENETICS is a fast-paced, high-growth health-tech company. Combining deep expertise in life sciences, medical disciplines and mathematical modeling, we bring to market data analytics solutions to support healthcare professionals in better diagnosing and treating patients. Today SOPHiA’s technologies are trusted by over 1000 leading hospitals worldwide, all connected to each other and motivated by the goal of providing better outcomes to all patients.

In our mission to democratize Data-Driven Medicine, we are looking for passionate and dedicated individuals to join our growing dynamic team.