An exciting opportunity has been created for a talented safety data scientist to work on methods to characterise and quantify the potential safety liabilities of drug targets. The position is funded by the Open Targets initiative which is a public-private initiative between EMBL-EBI, GlaxoSmithKline, BMS, Takeda, Sanofi and the Sanger Institute to generate and integrate evidence on the validity of biological targets for drug development.
Based in the ChEMBL Team at the European Bioinformatics Institute (EMBL-EBI) the appointee will work with the Open Targets partners to curate data and develop pipelines that will help to inform on the potential safety liabilities of biological targets into the Open Targets Platform.Your roleReporting to the ChEMBL team leader, you will have excellent attention to detail, strong communication skills and be able to interact with technical experts as well as scientists seeking solutions to their "real world" problems. The specific job responsibilities include:
- To develop and validate pipelines for identifying and quantifying potential safety liabilities of targets by utilising a variety of resources such as ChEMBL, clinical trials data, the scientific literature, adverse events reports;
- Curate relevant data relating to target safety liabilities from a variety of sources such as the scientific literature, prescribing information, validated web resources;
- Develop statistically robust analysis methods;
- Work with the Open Targets partners to assess, prioritise, validate and refine the resulting methods;
- To work with Open Targets core team to integrate the data and workflows into the Open Targets Platform.