The Nagy Lab at LBI-RUD, the Ludwig Boltzmann Institute for Rare and Undiagnosed Diseases in Vienna, seeks to fill the open the position of a
PART-TIME TECHNICAL ASSISTANT, 50% (reference code: #TA2020VN)
Our group focuses on identifying genetic causes of rare disorders affecting the development and function of the nervous system (Nagy, V. et al., NeurolGenet 2019, Nagy, V. et al., Cell Cycle 2015 and Nagy, V. et al., JNeurosci, 2006). Our studies utilize a wide variety of next generation sequencing technologies, microscopic imaging tools, biochemical, cellular and molecular techniques.
The group is looking for a highly motivated and well-organized Technical Assistant, who will be preparing samples for whole-exome sequencing (WES), analyzing/interpreting WES data, and prioritizing potentially disease-causing variants for further functional analysis. This position is suited for individuals who are interested and have experience in genetics, neurology, neuro-development, and bioinformatics and who enjoy working closely with clinicians and wet-bench researchers.
Tasks and responsibilities include:
- Sample preparation for next generation sequencing
- Bioinformatical analysis of whole-exome sequencing data
- Prioritization of potentially deleterious variants
- Segregation of variants within family pedigrees
- Documentation, interpretation and reporting of results