The Laboratory of Pathology, National Cancer Institute, Bethesda, MD is seeking a software developer who will be responsible for developing, modifying and maintaining a laboratory information system in coordination with the scientific and technologist staff. As part of the NCI-COMPASS program the Laboratory of Pathology currently has various genomic assays and is in the process of developing an expansive multiomics program which includes clinical-grade whole genome sequencing, whole transcriptome sequencing, and other genomic characterization modalities. A centralized way of collecting, extracting, and presenting this very large volume of data is needed in order to maximize the efficiency of clinical and research work and to meet regulatory requirements.
Specific duties will include:
Developing and presenting iterations of an information system based on cBioportal which will be used by molecular pathologists, technologists, and clinicians to:
-Store clinically relevant information (cancer type, metastatic site, etc)
-Link components to specific cases (eg previously resulted reports, scanned slide images, etc)
-Make clinical case components available for review during clinical conferences
-Extract information for analytical purposes including quality assessment metrics such as turnaround time, rates of specific mutations in a subset of specimens, etc
-Populate raw genomics data generated by the lab, ability to filter, query and linking with patient records.
-Serving as a member of a team of computer/bioinformatics scientist and engineers that design, develop and/or modify existing software to help solve scientific computing problems.
-Close interaction with staff to identify and implement their information system needs.
-Assisting in improving specimen and signout workflow.
-Managing interfacing with laboratory instrumentation.