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Senior Clinical Laboratory Technologist I – NYS license required


New York Genome Center

Job Location

101 Avenue of the Americas
New York, NY 10013
United States

Job Description

We are looking for a highly motivated, independent but team-oriented Senior Clinical Laboratory Technologist I to join our team. Our clinical laboratory incorporates many processes, applications, and specialized techniques along with the use of various types of instrumentation to perform cutting-edge tests in the areas of genetics and oncology; all of which aids in patient care. This position will allow the Senior Clinical Laboratory Technologist I to perform advanced, molecular-based skillsets, interpret complex data, and effectively troubleshoot while adhering to Clinical Laboratory Improvement Amendments (CLIA) guidelines.

Key Responsibilities:

Perform a variety of complex clinical laboratory procedures including nucleic acid extraction and quantification, PCR, Sanger sequencing, and next-generation sequencing with limited supervision;
Perform both manual and automated techniques to accomplish high volume sample processing;
Participate in equipment maintenance, QC/QA, and proficiency testing procedures;
Provide detailed, accurate and legible documentation associated with test results, maintenance records, and quality control;
Effectively and proactively analyze and present experimental results and determine next steps;
Troubleshoot assays independently;
Validate new assays;
Complete other laboratory tasks as assigned.

Position Requirements

Bachelor of Science degree required, biology preferred, other related majors will also be considered.
NYS Clinical Laboratory Technologist License (full or restricted to Molecular Diagnosis) required.
At least five years of experience in a clinical NGS genetics laboratory required, or 6+ years of equivalent relevant experience;
Familiarity with next generation sequencing on the Illumina platform required.
Demonstrates Advanced Excel skills (chart, formula manipulations) and familiarity with other data analysis tools, such as Mutation Surveyor, SeqScanner, etc.
Familiar with designing and ordering primers for variant confirmations (Sanger and qPCR);
Detail oriented and able to exercise independent judgment.
Excellent written and oral communication skills.
Must be available to work 5 days per week, including Saturdays as needed. However, we do not anticipate that Saturday work will be required every week.


Technical and Professional Skills: Consistently demonstrates skills and knowledge relevant for current role; strives to expand the depth and breadth of technical and professional skills; works with a high level of integrity; exhibits focus and discipline; appropriately prioritizes, manages expectations and delivers on commitments.
Collaborative & Communicative: Models collaboration and teamwork; brings out the best in others; effectively works with all levels, internally and externally; respects and embraces diversity of perspective; communicates clearly and listens carefully; uses good judgment as to what to communicate and when to do so.
Adaptable & Innovative: Adaptable and embraces change; develops new insights and pursues improvements and efficiency; fosters exchange of new ideas and willing to challenge the status quo; takes initiative and is solution-oriented; engages in work with passion and curiosity.


The pay range for this position is $80-110k per year; base pay offered may vary depending on job-related knowledge, skills, and experience. In addition, NYGC offers a full range of medical, financial, and other benefits as well as generous time off.

FLSA Status – Exempt

This position is not eligible for visa sponsorship or relocation assistance.

About Our Organization

About the Clinical Lab

The New York Genome Center (NYGC) has a state-of-the-art clinical diagnostic laboratory that utilizes next-generation sequencing technology to perform cutting-edge tests in the areas of genetics and oncology. The Clinical Laboratory is accredited by the Clinical Laboratory Improvement Amendments (CLIA) and the Clinical Laboratory Evaluation Program of the New York State Department of Health (CLEP). It is licensed to perform clinical testing in all fifty (50) of the United States and the District of Columbia. The laboratory participates in the College of American Pathologists (CAP) proficiency testing.

The Lab offers a variety of tests including Whole Genome Sequencing (WGS) and Whole Exome Sequencing (WES). Oncology Testing is available for patients with hematological malignancies and solid tumors. Genetic Testing is available for patients with undiagnosed diseases as well as individuals who are seeking predispositional genetic testing. NYGC is the first clinical laboratory offering New York State-approved clinical whole genome and transcriptome tests for cancer, and the first clinical laboratory offering New York State (NYS)-approved clinical WGS tests for undiagnosed disease and for predispositional genetic screening.

About the New York Genome Center

The New York Genome Center (NYGC) is an independent, nonprofit, academic research organization dedicated to advancing genomic research. NYGC scientists and staff are furthering new approaches to diagnosing and treating neurological diseases and cancer through their unique capabilities in whole genome sequencing, RNA sequencing, state-of-the art analytics, and the development of genomic tools. NYGC concentrates specifically on disease-based research in the following areas: neuropsychiatric disease (autism, schizophrenia, bipolar); neurodegenerative disease (ALS, Alzheimer’s, Parkinson’s, Huntington’s), and cancer.

Located in Lower Manhattan, the New York Genome Center was founded by and remains closely affiliated with the leading academic medical centers and research universities in the New York region, engaging in research projects with and for these institutions. Essential to our collaborative work is an outstanding faculty, whose members typically hold a joint appointment at NYGC and a partner university. They support our scientific mission by conducting independent research in areas of mutual interest to us and the wider scientific community.

Please note: We care greatly about our employees’ wellbeing, so NYGC has moved to a fully COVID-19 vaccinated work environment. You must be vaccinated against COVID-19 to work at NYGC, even if you are working partially remotely. If you are selected to interview for this role, we will explain our vaccination policy (including medical and religious exemptions) and ensure you are comfortable moving forward with further interviews.

Equal Opportunity

Diversity, equity, and inclusion are central to NYGC’s core mission. We strive to create a workplace environment that is welcoming and fair to all regardless of race, ethnicity, gender, sexual orientation, physical ability, or religion. We believe that when people of various backgrounds, life experiences, and perspectives work together in an inclusive and equitable environment we gain new and valuable perspectives that otherwise would have been missed. Valuing and supporting all NYGC employees as individuals while helping them realize their full potential is critical to promoting greater collaboration, innovation, and discovery – fostering a sense of belonging for our greatest strength, our people. We recognize that there is still work to be done that will require sustained commitment from the entire organization.

The New York Genome Center is a VEVRAA Federal Contractor. All qualified applicants will receive consideration for employment and will not be discriminated against on the basis of race, creed, color, gender, religion, national origin, sexual orientation, age, disability, genetic predisposition or carrier status, protected veteran or military status, domestic violence victim status, partnership status, caregiver status, alienage or citizenship status, marital status, or any other characteristic protected by applicable law. NYGC takes affirmative action in support of its policy to hire and advance in employment individuals who are minorities, women, protected veterans, and individuals with disabilities.