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Sr. Scientist

Organization

Ideal Search Services LLC

Job Location

x
San Francisco, CA 95054
United States

Salary

DOE

Benefits

Company paid healthcare, Equity, Flexible work environment, Growth opportunity, Great culture.

Job Description

The Senior Scientist reports directly to the Chief Scientific Officer and is responsible for leading assay development. Given the mutation rate of the SARS-CoV-2 virus, the Scientist will regularly monitor and conduct ongoing surveillance of variants and ensure assay sensitivity remains uncompromised, as well as execute any necessary adjustments to the assay to maintain specificity. Duties include, but are not limited, to: providing technical information and experimental assay design; data analysis and management; and instrument & project trouble-shooting.
• Leading design and execution of experiments
• Mentoring junior staff and developing scientist team
• Setting goals and prioritizing activities to reach assay development milestones
• Independently leading assay development team
• Making informed decisions regarding assay development pathway
• Reporting to CSO with results and data to inform company development direction
• Supporting the assay development team in the following:
o Time management and prioritization
o Providing feedback on experimental plans
o Executing multiple experiments in parallel
o Supporting assay development for new targets and multiplexed detection
o Optimizing assay performancce (signal output, primer affinity, time to result, sensitivity, etc.)
Daily/Monthly Responsibilities
• Performing laboratory R&D to push company's technology platform forward:
• Isothermal amplification, RT-LAMP, RT-PCR
• LAMP primer design
• Assay optimization
• Sample preparation
• Staying up to date on the in vitro diagnostic scientific literature and commercial space
• Working closely with a multidisciplinary team
• Working with archived clinical and analytical samples in a BSL-2+ laboratory
• Performing benchwork and laboratory experiments with company's prototype and commercial products
• Conducting new product development in a regulated environment
• Maintaining laboratory records in company's quality management system
• Supervising the work of research associates that may be hired in the near term
• Advising management and operations on requirements for material purchases for manufacturing
• Communicating with the Chief Technology Officer to ensure assay integration with hardware and software teams

Requirements

Minimum Requirements & Qualifications
• PhD in molecular biology, bioengineering, or a related field with a focus on development of molecular diagnostics, plus additional experience (preferably in industry) as outlined below
• Experience in a post-doctoral position OR
• Several years’ experience in industry in a senior scientist position working on LAMP-based application
• Demonstrated ability to guide and mentor staff and team
• Ability to work independently and take initiative to learn new skills and concepts
• Demonstrated ability to work in a fast-moving team environment
• Experience with performing general laboratory duties such as preparing reagents and basic maintenance of equipment
• Exemplary communication skills and ability to work on a multidisciplinary team
• Knowledge of statistical methods for experimental design and analyses
Preferred Qualifications
• Experience writing grants
• Hands-on experience with RT-LAMP, RT-PCR, and other amplification methods
• Familiarity with LAMP primer design and basic bioinformatics tools (BLAST, Clustal)
• Experience working within a regulated environment (e.g., ISO 9001, 13485)
• Understanding of fluorescence and FRET
• Experience with intellectual property protections (US utility patents)

How to Apply

Forward your CV to:

Robert Natowitz
Ideal Search Services LLC
[email protected]

About Our Organization

The company is a Bay Area bioscience startup developing a world-changing point-of-care and at-home diagnostics platform for personalized medicine. Their mission is to expand access to rapid, lab-quality testing and empower individuals to monitor their own health conveniently and inexpensively. They are committed to our employees, our customers, our community, and the environment.