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Automation Scientist/Engineer, Sample Prep Biochemistry


Pacific Biosciences

Job Location

1305 O’Brien Dr.
Menlo Park, CA 94025
United States

Job Description

Automation Scientist/Engineer, Sample Prep Biochemistry

Pacific Biosciences seeks a highly skilled and creative Automation Scientist or Engineer to drive implementation of automation solutions across our core front-end sample preparation products for the Pacific Biosciences SMRTTM (single molecule, real-time) sequencing platforms. The primary objectives of the team are to develop highly scalable, user-friendly, products and protocols that increase system throughput. The successful candidate will develop and implement automation workflows to support library preparation across different application areas. A strong working knowledge of genomic DNA extraction, industry-standard sample prep practices (NGS), and sequencing applications is essential. The successful candidate will be working in a fast-paced and energetic environment, interacting with scientists and engineers with diverse backgrounds.

Key responsibilities:

  • Innovation to improve Pacific Biosciences SMRTTM sequencing sample preparation methods and products
  • Work directly with scientists to understand protocols and translate those requirements into specifications for automation solutions
  • Develop high throughput automation protocols with goal of turnaround time optimization and minimization of human intervention points
  • Train users, troubleshoot, optimize workflow and provide ongoing support for end users
  • Analysis, interpretation and troubleshooting experimental results


  • B.S. or M.S. degree in Bioengineering, Engineering, Biochemistry, Molecular Biology, or related field
  • 2+ years of hands-on experience with operating and programming liquid handling robotics platforms, preferably Hamilton STAR liquid handlers
  • Experience in development of automated next-generation sequencing protocols and/or standard molecular biology techniques (nucleic acid isolation and purification, DNA quantitation, PCR, etc.)
  • Strong quantitative, troubleshooting and problem solving skills
  • Good communication and collaborative skills
  • Enjoy working closely with others as a member of an interdisciplinary team
  • Prior experience in the biotechnology industry highly desirable
  • Familiarity with Product Development process desirable

All listed tasks and responsibilities are deemed as essential functions to this position; however, business conditions may require reasonable accommodations for additional tasks and responsibilities.

All qualified applicants will receive consideration for employment without regard to race, sex, color, religion, national origin, protected veteran status, or on the basis of disability, gender identity, and sexual orientation.

About Our Organization

PacBio is a leading provider of high quality, long-read sequencing platforms.