The study said that Cologuard was an "inefficient screening option" for colorectal cancer given its cost as compared to other CRC screening methods.
After reviewing more than 100 studies, the panel issued recommendations focused on women with a personal or family history of BRCA1/2-related cancers or high-risk ancestry.
The study said that a revision of USPSTF's guidelines would lead to more equitable lung cancer screening for African American smokers at high risk for the disease.
The agency continues to recommend screening for all individuals ages 15 to 65, and has added its support for preexposure prophylaxis in high-risk populations.
By focusing too heavily on family history, the Preventive Services Task Force is missing many opportunities for prevention, patient advocates, industry players, and researchers say.
The firm has struggled in the past to convince payors of its test's clinical utility but remains dedicated to convincing the field that Epi proColon can help patients by closing CRC screening gaps.
In response to public comment on draft recommendations published last year, the USPSTF changed course and retained cotesting as an option.
The American Cancer Society today lowered the recommended age for screening patients at average risk for the disease to 45 from 50 years old.
The USPSTF said that men aged 55 to 69 should decide in discussions with their clinicians whether to undergo periodic PSA screening.
Currently available screening methods have not been shown to reduce mortality in the general population, USPSTF said.