GenDx NGStrack, TRKengine for chimerism monitoring
Genome Diagnostics (GenDx) has launched its NGStrack reagents and TRKengine software for monitoring chimerism in a recipient after a stem cell transplant by next-generation sequencing. NGStrack uses 32 indel markers to distinguish between donor and recipient, which cover 362 nucleotide positions across 18 chromosomes, and only requires small amounts of DNA. The TRKengine software interprets the markers and determines the percentage of chimerism. The products are compatible with Illumina sequencing platforms.