NEW YORK (360Dx) – A protein shed into the cerebrospinal fluid acts as a marker of inflammation during early Alzheimer's disease development, researchers from Germany and the US have found.

Alzheimer's disease is thought to be driven by the accumulation of amyloid-beta, which then leads to a cascade of events, including the development of plaques, to bring on cognitive decline. At the same time, inflammatory events and the activation of microglia are suspected to have a role in disease development, though how they fit into that progression has been unclear.

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