UK Researchers Validate Biomarker Test for Liver Injury Due to Paracetamol Overdose

Nov 17, 2017

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NEW YORK (360Dx) – A research team led by the University of Edinburgh and the University of Liverpool has shown that a combined biomarker model consisting of microRNA-122 (MiR-122), keratin-18 (K18), and high mobility group box-1 (HMGB1) showed better sensitivity and specificity than alanine aminotransferase (ALT) concentration, a gold standard marker, in detecting liver injury from paracetamol overdose.

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