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NEW YORK (GenomeWeb) – A international group of researchers led by the Georgetown Lombardi Comprehensive Cancer Center has developed an immunohistochemistry assay for the STAG2 gene, which they believe can act as a biomarker for papillary non-muscle-invasive bladder cancer (NMIBC).

Specifically, the team found that tumors that uniformly express STAG2 are twice as likely to recur and progress to muscle invasion as tumors that exhibit complete or mosaic loss of STAG2 expression.

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