Drug Discovery & Development

News on drug screening, clinical trials, companion diagnostics, immunotherapy, & personalized therapies in genetics, genomics, and molecular diagnostics.

FDA Approves Epizyme's Tazverik, Roche CDx for EZH2-Mutated Follicular Lymphoma Patients

The accelerated approval is based on results from two cohorts of a Phase II, single-arm trial in which EZH2-mutated patients had an overall response rate of 69 percent.

Adaptive Eyes NGS-Based Test for T Cell Response in COVID-19

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The diagnostics firm is conducting a 1,000-person study to find T cell profiles associated with the immune response to COVID-19 and recovery from the disease.

Axovant, Invitae Launch Free Genetic Testing Program for Lysosomal Storage Diseases

Invitae will provide free genetic testing on a 53-gene panel and counseling to patients suspected of having an LSD to facilitate earlier diagnosis and appropriate treatment.

FDA Releases List of Evidence-Based PGx Variants

The agency compiled the evolving list by drawing on information from drug labeling and the published literature and is asking stakeholders to provide feedback.

Adaptive Biotechnologies, Genentech Partner on MRD Testing in Venetoclax Clinical Trial

Genentech will use Adaptive's ClonoSeq assay for MRD testing in a CLL study. Adaptive will receive upfront and sample testing payments of undisclosed amounts.

Dec 04, 2019

PGDx Gets IDE For Tissue NGS Test in Merck Immunotherapy Trial

Nov 27, 2019

HalioDx, OSE Immunotherapeutics Collaborate on Immune Biomarkers for NSCLC Treatment

Nov 19, 2019

HalioDx, Kite Pharma Extend Biomarker Collaboration

Nov 18, 2019

Centogene to Provide Diagnostic Testing Services for PTC Therapeutics Gene Therapy Program

Nov 13, 2019

Interpace Diagnostics Reports 33 Percent Q3 Revenue Growth; Changes Name to Interpace Biosciences

Nov 07, 2019

Centogene Prices US IPO at $14 per Share

Oct 17, 2019

Centogene Files to Go Public in US

Oct 10, 2019

FDA Issues Final Guidance on IVD Reviews for Investigational Cancer Drug Trials

Oct 10, 2019

UTC Labs, Principals Agree to Pay $42.6M in PGx Testing Fraud Case

Aug 16, 2019

Xylonix, BioGemex Ink MOU to Develop Point-of-Care Cancer Immunotherapy-Response Diagnostic

Aug 13, 2019

Adaptive Biotechnologies Q2 Revenues Rise 91 Percent

Jul 24, 2019

Gray Foundation Awards $25M in Cancer Research Grants

Jun 24, 2019

SpeeDx, GSK Sign Test Supply, Development Deal

May 07, 2019

Adial Pharmaceuticals, Eurofins Scientific Partner on CDx for Alcohol Use Disorder Drug

Apr 24, 2019

Macrogen, Exosome Plus Ink MOU, Deal for Exosome Isolation Kits

Feb 27, 2019

Danaher Prices $2.76B Offering of Common, Preferred Stock

Sep 26, 2018

Konica Minolta Launches Precision Medicine Business

Mar 14, 2018

Exosome Diagnostics, Intezyne to Develop Exosomal RNA Assay for Novel CRP Inhibitor

Feb 09, 2018

Q-State Subsidiary Buys Claritas Assets, Plans Relaunch of Lab to Support Drug Discovery Programs