NEW YORK (360Dx) – Genomic Health announced last week the full launch of what it calls the Oncotype DX AR-V7 Nucleus Detect test, an assay designed and performed by circulating tumor cell firm Epic Sciences.

The test detects the AR-V7 splice variant of the androgen receptor protein in the nucleus of isolated CTCs in order to identify which men with metastatic castration-resistant prostate cancer are more likely to respond to treatment with an androgen receptor-signaling inhibitor (ARSI) therapy, and which would be better served by chemotherapy.

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Dec
03
Sponsored by
Advanced Cell Diagnostics

This webinar will demonstrate how a research team at the National Institutes of Health evaluated a novel in situ hybridization approach and applied it to study splice variants related to schizophrenia.

Dec
04
Sponsored by
Sophia Genetics

This webinar will discuss the use of clinical-grade exome analysis application in complex case investigations.

Dec
06

Rhythm Pharmaceuticals and Genomenon will discuss their efforts to assemble a database of mutations associated with rare genetic disorders of obesity, and how this was optimized to facilitate a deep understanding of the variant landscape of melanocortin-4 receptor (MC4R)-pathway genes. This database may help identify MC4R-pathway deficient individuals who might benefit from future precision therapies.