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The researchers used multiple-reaction monitoring mass spec to create a more sensitive assay to AFP-L3, a protein marker for hepatocellular carcinoma.
They found that cMyC protein was more abundant than cardiac troponin in heart disease patients and that it could be used to quickly rule out heart attack.
The company will work with medical faculties of the universities of Greifswald and Rostock to develop Dx tools for personalized, immune-based treatments.
The initial focus will be on Zika and chikingunya, and will leverage iBio's antigen and antibody manufacturing capabilities for product prototype development.
The company is now commencing a trial of the test platform in 250 patients to generate more data while it considers how to best commercialize it.
They have begun field testing near-infrared spectroscopy as an alternative to PCR and ELISA for routine pathogen screening in mosquitoes.
The company has partnered with several major medical centers to recruit several thousand subjects to compare its test to current mainstays.
The platform, which its developers said is well suited to point-of-care testing, uses fluorescent polymers to distinguish between samples from cases and controls.
To detect clinically relevant levels, the magneto-optic system measured magnetic nanocrystals in rabbit blood created by the malaria parasite.
Years after several high-profile failures, activity is up among researchers looking to multi-analyte protein assays for monitoring and detection of the disease.