The US DOJ had alleged Boston Heart Diagnostics conspired to pay doctors kickbacks that were disguised as investment returns.
The company decided to settle the complaint in order to avoid "lengthy and distracting litigation," but denies any wrongdoing.
The federal government said GenomeDx billed Medicare for its Decipher Biopsy prostate cancer genome classifier on behalf of patients who didn't need the test.
As part of the legal settlement, Akers Bio will pay $930,000 to Pulse Health, and it has agreed to a permanent injunction against selling a disposable breath test.
The judgment settles charges that Calloway Laboratories provided free testing supplies to physicians in exchange for urine test referrals.
By early 2020, the UK company plans to develop a version of its Iona test that uses Illumina's sequencing technology.
The US Attorney's Office, Western District of Pennsylvania alleged the doctors received improper payments for referrals from drug testing lab Universal Oral Fluid Laboratories.
The DOJ alleged Biotheranosics promoted and performed its Breast Cancer Index test for patients who had not been in remission for five years and who had not been taking tamoxifen.
The company will pay the US $33.2 million to settle allegations that it caused hospitals to submit false claims to federal healthcare programs.
Company Founder and CEO Elizabeth Holmes has agreed to pay a $500,000 penalty. She is also barred from serving as an officer or director of a publicly traded company for 10 years.