NEW YORK (360Dx) – A urine-based diagnostic test for kidney transplant rejection provides new options for nephrologists who normally need to do tissue biopsies that are painful for patients, according to its maker.

The Numares renalTX-Score test employs four biomarkers — alanine, citrate, lactate, and urea — and eliminates the need for a tissue biopsy on patients, the firm, Numares, said.

Individually they are “mediocre biomarkers,” but taken in tandem they provide a robust evaluation of the risk for kidney rejection, Numares CTO Maximilian Zucker said in an interview.