NEW YORK (GenomeWeb) – Researchers have developed a polygenic hazard score that they said does a better job than existing methods of identifying older adults with normal cognition who are at the highest risk of developing Alzheimer’s dementia.

The genetic prediction technique, developed by researchers at the University of California, San Francisco, and the University of California, San Diego, combines the effects of more than 31 genetic variants, most of whom, by themselves, are associated with only a small risk of Alzheimer’s disease, the researchers said.